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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Zinc Finger E-box-Binding Homeobox 1
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Zinc Finger E-box-Binding Homeobox 1
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Homeodomain Proteins > Zinc Finger E-box-Binding Homeobox 1

Preferred term

Zinc Finger E-box-Binding Homeobox 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • NIL 2 A Zinc Finger Protein
  • NIL-2-A Zinc Finger Protein
  • TCF8 Protein
  • Transcription Factor 8
  • Transcription Factor, Zeb1
  • Zeb1 Transcription Factor

Scope note

  • A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071799

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