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Biological Factors > Intercellular Signaling Peptides and Proteins > Wnt Proteins > Wnt-5a Protein
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Wnt Proteins > Wnt-5a Protein
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Wnt Proteins > Wnt-5a Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Wnt-5a Protein

Preferred term

Wnt-5a Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Wingless Type MMTV Integration Site Family, Member 5A
  • Wingless-Type MMTV Integration Site Family, Member 5A
  • Wnt5a Protein

Scope note

  • A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000071818

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 4/15/16