Concept information
Preferred term
Fibrillins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Fibrillin
Scope note
- A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
History note
- 2017; use FIBRILLIN 1985-2016
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000071837
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