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Concept information

Preferred term

NF-KappaB Inhibitor alpha  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • IKappaB alpha
  • IKappaB-alpha
  • IKappaBalpha
  • I Kappa B alpha Protein
  • I Kappa B-alpha Protein
  • Major Histocompatibility Complex Enhancer Binding Protein MAD3
  • Major Histocompatibility Complex Enhancer-Binding Protein MAD3
  • p40 Protein (IKappaB-alpha)

Scope note

  • An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.

History note

  • 2017 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072000

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