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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic Helix-Loop-Helix Transcription Factors > Transcription Factor HES-1
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic Helix-Loop-Helix Transcription Factors > Transcription Factor HES-1

Preferred term

Transcription Factor HES-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Hairy and Enhancer of Split 1 Protein
  • Hairy Like Transcription Factor
  • Hairy-Like Transcription Factor
  • Transcription Factor, Hairy-Like

Scope note

  • A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000072056

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/27/16