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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Patched Receptors > Patched-2 Receptor
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Patched Receptors > Patched-2 Receptor

Preferred term

Patched-2 Receptor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Patched 2 Protein
  • Patched-2 Protein
  • Patched Homolog 2
  • Patched Homolog-2
  • Patched Receptor 2
  • Patched Receptor-2
  • PTCH2 Protein

Scope note

  • A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.

History note

  • 2017 (1996)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072082

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