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Concept information

Preferred term

Jagged-1 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Alagille Syndrome Protein
  • Antigen, CD339
  • CD339 Antigen
  • Jagged 1
  • Jagged-1
  • Jagged1 Protein
  • Serrate 1 Protein
  • Serrate-1 Protein
  • Serrate1 Protein

Scope note

  • A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.

History note

  • 2017 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072100

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