Concept information
Preferred term
Ku Autoantigen
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, G22P1
- Antigen, Ku
- G22P1 Antigen
- Heterodimer, Ku
- Ku Antigen
- Ku Heterodimer
- Ku Protein
Scope note
- An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
History note
- 2017 (1986)
In other languages
-
Finnish
-
Swedish
-
G22P1 antigen
-
Ku protein
-
Ku70 antigen
-
KU80 antigen
URI
http://www.yso.fi/onto/mesh/D000072200
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