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Concept information

Preferred term

Ku Autoantigen  

Type

  • Topical Descriptor

Entry terms

  • Antigen, G22P1
  • Antigen, Ku
  • G22P1 Antigen
  • Heterodimer, Ku
  • Ku Antigen
  • Ku Heterodimer
  • Ku Protein

Scope note

  • An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

History note

  • 2017 (1986)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072200

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