Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Homer Scaffolding Proteins

Preferred term

Homer Scaffolding Proteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Homer Protein
  • Homer Proteins
  • Protein, Homer
  • Proteins, Homer

Scope note

  • Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.

History note

  • 2017 (1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072233

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/11/16, last modified 6/30/21