Concept information
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Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
...
Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
...
Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
Preferred term
ERG1 Potassium Channel
Type
-
Topical Descriptor
Broader concept
Entry terms
- Ether A Go Go Related Potassium Channel 1
- Ether-A-Go-Go-Related Potassium Channel 1
- Potassium Voltage-Gated Channel, Subfamily H, Member 2
Scope note
- One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
History note
- 2017 (2001)
In other languages
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Finnish
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Swedish
URI
http://www.yso.fi/onto/mesh/D000072237
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