Concept information
Preferred term
NIMA-Interacting Peptidylprolyl Isomerase
Type
-
Topical Descriptor
Broader concept
Entry terms
- Isomerase, Pin1 Peptidylprolyl
- Peptidyl Prolyl Cis Trans Isomerase Pin1
- Peptidyl-Prolyl Cis-Trans Isomerase Pin1
- Peptidylprolyl Isomerase, Pin1
- Pin1 Peptidylprolyl Isomerase
- PIN1 Protein
Scope note
- A highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1.
History note
- 2017 (1996)
In other languages
URI
http://www.yso.fi/onto/mesh/D000072340
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