Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Preferred term
Syk Kinase
Type
-
Topical Descriptor
Broader concept
Entry terms
- Kinase, Spleen Tyrosine
- Kinase, SYK Tyrosine
- Spleen Tyrosine Kinase
- SYK Tyrosine Kinase
- Tyrosine Kinase, Spleen
- Tyrosine Kinase, SYK
Scope note
- An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
History note
- 2017 (1992)
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D000072377
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