Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Pregnancy Proteins > Placenta Growth Factor
Biological Factors > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Placenta Growth Factor
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Placenta Growth Factor
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Placenta Growth Factor

Preferred term

Placenta Growth Factor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Placenta Growth Factor, PLGF 1 Isoform
  • Placenta Growth Factor, PLGF-1 Isoform
  • Placenta Growth Factor, PLGF 2 Isoform
  • Placenta Growth Factor, PLGF-2 Isoform
  • Placenta Growth Factor, PLGF 3 Isoform
  • Placenta Growth Factor, PLGF-3 Isoform
  • Placenta Growth Factor, PLGF 4 Isoform
  • Placenta Growth Factor, PLGF-4 Isoform

Scope note

  • An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

History note

  • 2017 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072483

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 7/5/16