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Amino Acids, Peptides, and Proteins > Proteins > Antiviral Restriction Factors > Interferon-Induced Helicase, IFIH1
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Nucleotidyltransferases > RNA Nucleotidyltransferases > RNA Helicases > DEAD-box RNA Helicases > Interferon-Induced Helicase, IFIH1

Preferred term

Interferon-Induced Helicase, IFIH1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Autoantigen, CADM-140
  • CADM 140 Autoantigen
  • CADM-140 Autoantigen
  • Helicard
  • IFIH1 Protein
  • Interferon Induced Helicase C Domain Containing Protein 1
  • Interferon-Induced Helicase C Domain-Containing Protein 1
  • Interferon Induced with Helicase C Domain 1
  • Melanoma Differentiation Associated Protein 5
  • Melanoma Differentiation-Associated Protein 5

Scope note

  • A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.

History note

  • 2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000072640

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