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Concept information

Preferred term

PTB-Associated Splicing Factor  

Type

  • Topical Descriptor

Entry terms

  • Polypyrimidine Tract Binding Protein Associated Splicing Factor
  • Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
  • PSF Splicing Factor
  • SFPQ Protein
  • Splicing Factor Proline Glutamine Rich Protein
  • Splicing Factor Proline-Glutamine Rich Protein
  • Splicing Factor, PSF

Scope note

  • An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.

History note

  • 2017 (1993)

In other languages

URI

http://www.yso.fi/onto/mesh/D000072670

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