Concept information
Preferred term
PTB-Associated Splicing Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Polypyrimidine Tract Binding Protein Associated Splicing Factor
- Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
- PSF Splicing Factor
- SFPQ Protein
- Splicing Factor Proline Glutamine Rich Protein
- Splicing Factor Proline-Glutamine Rich Protein
- Splicing Factor, PSF
Scope note
- An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.
History note
- 2017 (1993)
In other languages
-
Finnish
-
PTB:hen liittyvä pujontatekijä
URI
http://www.yso.fi/onto/mesh/D000072670
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