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Biological Factors > Intercellular Signaling Peptides and Proteins > Apelin
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Apelin
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Apelin

Preferred term

Apelin  

Type

  • Topical Descriptor

Broader concept

Scope note

  • A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response.

History note

  • 2018

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URI

http://www.yso.fi/onto/mesh/D000073861

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