Concept information
Preferred term
Triggering Receptor Expressed on Myeloid Cells-1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD354
- CD354 Antigen
- TREM 1 Protein
- TREM-1 Protein
Scope note
- An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
History note
- 2018
In other languages
-
Finnish
-
myeloisissa solu-1:issä ilmenevä aktivoiva reseptori
URI
http://www.yso.fi/onto/mesh/D000073871
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