Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4

Preferred term

Transcription Factor 4  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • TCF 4 Protein
  • TCF-4 Protein
  • TCF 4 Transcription Factor
  • TCF-4 Transcription Factor
  • TCF4 Transcription Factor
  • Transcription Factor, TCF-4
  • Transcription Factor, TCF4

Scope note

  • A basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000073940

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 2/27/17