Concept information
Preferred term
T-Cell Intracellular Antigen-1
Type
-
Topical Descriptor
Entry terms
- Intracellular Antigen-1, T-Cell-Restricted
- RNA Binding Protein TIA 1
- RNA-Binding Protein TIA-1
- T Cell Restricted Intracellular Antigen 1
- T-Cell-Restricted Intracellular Antigen-1
- TIA-1, RNA-Binding Protein
Scope note
- An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.
History note
- 2018
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D000074019
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