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Concept information

Preferred term

T-Cell Intracellular Antigen-1  

Type

  • Topical Descriptor

Entry terms

  • Intracellular Antigen-1, T-Cell-Restricted
  • RNA Binding Protein TIA 1
  • RNA-Binding Protein TIA-1
  • T Cell Restricted Intracellular Antigen 1
  • T-Cell-Restricted Intracellular Antigen-1
  • TIA-1, RNA-Binding Protein

Scope note

  • An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074019

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