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Concept information

Preferred term

ATP Binding Cassette Transporter, Subfamily B, Member 11  

Type

  • Topical Descriptor

Entry terms

  • ABCB11 Protein
  • ATP Binding Cassette Subfamily B Member 11
  • ATP Binding Cassette Transporter, Sub-Family B, Member 11
  • Bile Salt Export Pump
  • BSEP Protein

Scope note

  • ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).

History note

  • 2019 (2018)

In other languages

URI

http://www.yso.fi/onto/mesh/D000074020

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