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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Pumps > Cation Transport Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Pumps > Cation Transport Proteins > Organic Cation Transport Proteins > Solute Carrier Family 22 Member 5

Preferred term

Solute Carrier Family 22 Member 5  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Carnitine Cotransporter, Sodium-Dependent
  • Carnitine Transporter, High-Affinity
  • High Affinity Carnitine Transporter
  • High-Affinity Carnitine Transporter
  • OCTN2 Protein
  • Organic Cation Carnitine Transporter 2
  • Organic Cation-Carnitine Transporter 2
  • SLC22A5 Protein
  • Sodium Dependent Carnitine Cotransporter
  • Sodium-Dependent Carnitine Cotransporter
  • Transporter, High-Affinity Carnitine

Scope note

  • A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074058

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