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Concept information

Preferred term

MutS Proteins  

Type

  • Topical Descriptor

Entry terms

  • MutS Protein
  • Protein, MutS

Scope note

  • DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074080

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