Concept information
Preferred term
MutS Proteins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- MutS Protein
- Protein, MutS
Scope note
- DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
History note
- 2018
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D000074080
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