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Concept information

Preferred term

Sodium-Hydrogen Exchanger 3  

Type

  • Topical Descriptor

Entry terms

  • Na(+)-H(+) Exchanger 3
  • NHE 3 Protein
  • NHE-3 Protein
  • SLC9A3 Protein
  • Solute Carrier Family 9 Member 3

Scope note

  • A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition.

History note

  • 2018 (1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D000074083

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