Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Valosin Containing Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Acid Anhydride Hydrolases > Adenosine Triphosphatases > ATPases Associated with Diverse Cellular Activities > Valosin Containing Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > AAA Proteins > ATPases Associated with Diverse Cellular Activities > Valosin Containing Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Acid Anhydride Hydrolases > AAA Proteins > ATPases Associated with Diverse Cellular Activities > Valosin Containing Protein

Preferred term

Valosin Containing Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CDC48 Protein
  • Cell Cycle Protein CDC48
  • Cell Cycle Protein CDC48p
  • p97 Valosin Containing Protein
  • p97 Valosin-Containing Protein
  • Valosin-Containing Protein
  • Valosin-Containing Protein, p97
  • Valosine Containing Protein
  • Valosine-Containing Protein

Scope note

  • A highly-conserved AAA ATPase that functions in the biogenesis of the transitional ENDOPLASMIC RETICULUM and fragmentation and reassembly of the GOLGI APPARATUS during MITOSIS. It also functions in a complex with UFD1L and NPLOC4 proteins to export misfolded ubiquitinated proteins from the endoplasmic reticulum and outer mitochondrial membrane to the cytoplasm for degradation by the PROTEASOME and also plays a role in AUTOPHAGY of ubiquitinated proteins. It occurs in neuronal INCLUSION BODIES from patients with AMYOTROPHIC LATERAL SCLEROSIS and LEWY BODIES from PARKINSON DISEASE patients.

History note

  • 2018 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D000074405

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/2/17