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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Alcohol Oxidoreductases > NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases > Aldo-Keto Reductases
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Alcohol Oxidoreductases > Carbohydrate Dehydrogenases > Sugar Alcohol Dehydrogenases > Aldo-Keto Reductases

Preferred term

Aldo-Keto Reductases  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Aldo Keto Reductase Family
  • Aldo-Keto Reductase Family
  • Aldo Keto Reductase Superfamily
  • Aldo-Keto Reductase Superfamily

Scope note

  • A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074408

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