Concept information
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Oxidoreductases
Alcohol Oxidoreductases
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
Aldo-Keto Reductases
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Alcohol Oxidoreductases
Carbohydrate Dehydrogenases
Sugar Alcohol Dehydrogenases
Aldo-Keto Reductases
Preferred term
Aldo-Keto Reductase Family 1 Member C3
Type
-
Topical Descriptor
Broader concept
Entry terms
- 17 beta Hydroxysteroid Dehydrogenase Type 5
- 17-beta-Hydroxysteroid Dehydrogenase Type 5
- AKR1C3 Protein
- Dihydrodiol Dehydrogenase 3
Scope note
- Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.
History note
- 2018
In other languages
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Finnish
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aldoketoreduktaasi-perheen 1 jäsen C3
URI
http://www.yso.fi/onto/mesh/D000074425
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