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Concept information

Preferred term

Aldo-Keto Reductase Family 1 Member C3  

Type

  • Topical Descriptor

Entry terms

  • 17 beta Hydroxysteroid Dehydrogenase Type 5
  • 17-beta-Hydroxysteroid Dehydrogenase Type 5
  • AKR1C3 Protein
  • Dihydrodiol Dehydrogenase 3

Scope note

  • Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074425

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