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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Positive Regulatory Domain I-Binding Factor 1
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Positive Regulatory Domain I-Binding Factor 1
... > Enzymes and Coenzymes > Enzymes > Transferases > One-Carbon Group Transferases > Methyltransferases > Protein Methyltransferases > Positive Regulatory Domain I-Binding Factor 1

Preferred term

Positive Regulatory Domain I-Binding Factor 1  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • BLIMP1 Protein
  • B Lymphocyte Induced Maturation Protein 1
  • B Lymphocyte-Induced Maturation Protein 1
  • PRDI BF1 Protein
  • PRDI-BF1 Protein
  • PRDM1 Protein

Scope note

  • A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074462

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/2/17