Concept information
Preferred term
Solute Carrier Organic Anion Transporter Family Member 1B3
Type
-
Topical Descriptor
Entry terms
- Liver Specific Organic Anion Transporter 2
- Liver-Specific Organic Anion Transporter-2
- OATP1B3 Protein
- OATP8 Protein
- SLC21A8 Protein
- SLCO1B3 Protein
- Solute Carrier Family 21 Member 8 Protein
Scope note
- A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
History note
- 2018
In other languages
-
Finnish
-
liuennut kantaja orgaanisten anionien kuljetinperheen jäsen 1B3
-
liukoinen kantaja orgaanisten anionien kuljetinperheen jäsen 1B3
-
liukoinen kantaja orgaanisten anionien kuljettajaperheen jäsen 1B3
URI
http://www.yso.fi/onto/mesh/D000074542
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