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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > NADPH Oxidases > Dual Oxidases
Amino Acids, Peptides, and Proteins > Proteins > Flavoproteins > NADPH Oxidases > Dual Oxidases
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > NADH, NADPH Oxidoreductases > NADPH Oxidases > Dual Oxidases

Preferred term

Dual Oxidases  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Dual Oxidase
  • Duox Proteins
  • Oxidase, Dual
  • Proteins, Duox

Scope note

  • NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074623

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