Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > NADPH Oxidases > NADPH Oxidase 2
Amino Acids, Peptides, and Proteins > Proteins > Flavoproteins > NADPH Oxidases > NADPH Oxidase 2
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > NADH, NADPH Oxidoreductases > NADPH Oxidases > NADPH Oxidase 2

Preferred term

NADPH Oxidase 2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Chronic Granulomatous Disease Protein
  • CYBB Protein
  • Cytochrome B 245 Beta Chain
  • Cytochrome B-245 Beta Chain
  • GP91 PHOX Protein
  • GP91-PHOX Protein
  • NOX2 Protein

Scope note

  • An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074662

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 4/5/17