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Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Deubiquitinating Enzyme CYLD
Enzymes and Coenzymes > Enzymes > Deubiquitinating Enzymes > Deubiquitinating Enzyme CYLD

Preferred term

Deubiquitinating Enzyme CYLD  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CYLD Protein
  • Cylindromatosis, Deubiquitinating Enzyme
  • Cylindromatosis Protein
  • Deubiquitinating Enzyme Cylindromatosis

Scope note

  • A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.

History note

  • 2018

In other languages

  • ubikitinaasi CYLD

    Finnish

  • ubikitiiniä hajottava enstyymi CYLD
  • ubikitiiniä poistava enstyymi CYLD

URI

http://www.yso.fi/onto/mesh/D000074749

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/2/17