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... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein

Preferred term

Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • MALT1 Paracaspase
  • MALT 1 Protein
  • MALT-1 Protein
  • MALT1 Protein
  • Paracaspase
  • Paracaspase, MALT1

Scope note

  • A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000074884

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