Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Eye Proteins > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins

Preferred term

Bestrophins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Bestrophin
  • Bestrophin Family
  • Bestrophin Proteins

Scope note

  • A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000075002

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/30/21