Concept information
Preferred term
S100 Calcium Binding Protein A7
Type
-
Topical Descriptor
Broader concept
Entry terms
- Psoriasin
- S100 A7 Protein
- S100-A7 Protein
- S100A7 Protein
Scope note
- An S100 calcium binding protein that contains two EF HAND MOTIFS and also binds zinc. It is secreted via a non-classical secretory pathway and expressed by KERATINOCYTES and epithelial cells of the tongue. It has antimicrobial and immunomodulatory activities and is highly expressed in the skin of patients with PSORIASIS, as well as in bladder and skin epithelial carcinomas.
History note
- 2018
In other languages
-
Finnish
-
S100-A7-proteiini
-
S100A7-proteiini
URI
http://www.yso.fi/onto/mesh/D000075023
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