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Concept information

Preferred term

rhoC GTP-Binding Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ras Homolog Family Member C
  • rhoC GTPase

Scope note

  • A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000075024

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