Concept information
Preferred term
Myeloid Ecotropic Viral Integration Site 1 Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- Homeobox Protein MEIS1
- MEIS1, Homeobox Protein
- Meis 1 Protein
- Meis-1 Protein
- Meis1 Protein
- Meis1 Transcription Factor
- Transcription Factor, Meis1
Scope note
- A TALE-type homeodomain protein and transcription factor that functions as a regulator of PAX6 PROTEIN expression and as an activator of PLATELET FACTOR 4 gene expression. It is essential for hematopoiesis, differentiation of MEGAKARYOCYTES, and vascular patterning. It may also have a role in the induction of myeloid leukemias.
History note
- 2018 (1995)
In other languages
URI
http://www.yso.fi/onto/mesh/D000075064
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