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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Elongin
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Elongin

Preferred term

Elongin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Complex, Elongin
  • Elongation Factor, SIII
  • Elongin Complex
  • SIII Elongation Factor
  • SIII, Transcription Factor
  • TF-SIII
  • Transcription Factor SIII

Scope note

  • A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.

History note

  • 2018 (1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D000075065

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