Concept information
Preferred term
Leukocyte Immunoglobulin-like Receptor B1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD85
- Antigen, CD85J
- CD85 Antigen
- CD85J Antigen
- ILT2 Protein
- Immunoglobulin like Transcript 2 Protein
- Immunoglobulin-like Transcript 2 Protein
- Leukocyte Ig like Receptor B1
- Leukocyte Ig-like Receptor B1
- LILRB1
- LIR 1 Protein
- LIR-1 Protein
Scope note
- A receptor for HISTOCOMPATIBILITY ANTIGENS CLASS I that also functions as a receptor for the UL18 protein, an MHC class I homolog expressed by human CYTOMEGALOVIRUS. It consists of four Ig-like C2 domains and is expressed primarily by B-cells and MONOCYTES, as well as DENDRITIC CELLS; its interaction with MHC1 functions to down-regulate the immune response.
History note
- 2018
In other languages
URI
http://www.yso.fi/onto/mesh/D000075362
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}