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Concept information

Preferred term

Anoctamins  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Anoctamin
  • Protein Family, TMEM16
  • TMEM16 Protein Family
  • TMEM16 Proteins

Scope note

  • A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000075368

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