Concept information
Preferred term
Anoctamins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Anoctamin
- Protein Family, TMEM16
- TMEM16 Protein Family
- TMEM16 Proteins
Scope note
- A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
History note
- 2018
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000075368
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