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Concept information

Preferred term

Zinc Finger Protein Gli2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Gli2 Protein

Scope note

  • A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.

History note

  • 2018 (1997); use GLI2 PROTEIN 1997-2017

In other languages

URI

http://www.yso.fi/onto/mesh/D000075746

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