Concept information
Preferred term
Cell Adhesion Molecule-1
Type
-
Topical Descriptor
Broader concept
Entry terms
- CADM1 Protein
- IGSF4 Protein
- TSLC1 Protein
- Tumor Suppressor in Lung Cancer 1 Protein
Scope note
- A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
History note
- 2018
In other languages
-
Finnish
-
solun kiinnittymismolekyyli 1
-
solun pinnan tarttumismolekyyli 1
-
solun tarttumismolekyyli 1
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000075982
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