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Concept information

Preferred term

Cell Adhesion Molecule-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CADM1 Protein
  • IGSF4 Protein
  • TSLC1 Protein
  • Tumor Suppressor in Lung Cancer 1 Protein

Scope note

  • A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000075982

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 3/16/23