Concept information
Preferred term
Inhibitor of Growth Protein 1
Type
-
Topical Descriptor
Broader concept
Entry terms
- ING 1 Protein
- ING-1 Protein
- ING1 Protein
- p33ING Protein
Scope note
- A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
History note
- 2018
In other languages
-
Finnish
-
kasvuproteiini 1:n inhibiittori
URI
http://www.yso.fi/onto/mesh/D000076023
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