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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Ubiquitin-Specific Proteases > Ubiquitin-Specific Peptidase 7
Enzymes and Coenzymes > Enzymes > Deubiquitinating Enzymes > Ubiquitin-Specific Proteases > Ubiquitin-Specific Peptidase 7

Preferred term

Ubiquitin-Specific Peptidase 7  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • HAUSP Protein
  • Herpesvirus Associated Ubiquitin Specific Peptidase
  • Herpesvirus-Associated Ubiquitin-Specific Peptidase
  • Peptidase, Herpesvirus-Associated Ubiquitin-Specific
  • Ubiquitin-Specific Peptidase, Herpesvirus-Associated
  • USP7 Protein

Scope note

  • A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000076084

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