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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Disks Large Homolog 4 Protein
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Phosphate Group Acceptor) > Guanylate Kinases > Disks Large Homolog 4 Protein

Preferred term

Disks Large Homolog 4 Protein  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Discs Large Homolog 4 Protein
  • Postsynaptic Density Protein 95
  • PSD 95 Protein
  • PSD-95 Protein
  • PSD95 Protein
  • SAP 90 Protein
  • SAP-90 Protein
  • SAP90 Protein
  • Synapse Associated Protein 90
  • Synapse-Associated Protein 90

Scope note

  • A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.

History note

  • 2018

In other languages

URI

http://www.yso.fi/onto/mesh/D000076122

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