Concept information
Preferred term
Sp7 Transcription Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Osterix Protein
Scope note
- An Sp transcription factor that contains three CYS2-HIS2 ZINC FINGERS. It binds to GC RICH SEQUENCES and performs an essential function in regulating gene expression for differentiation of OSTEOBLASTS. Mutations in the SP7 gene are associated with type 12 OSTEOGENESIS IMPERFECTA.
History note
- 2018
In other languages
-
Finnish
-
Osterix
-
Osx
URI
http://www.yso.fi/onto/mesh/D000076182
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