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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Chromosomal Proteins, Non-Histone > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > Chromosomal Proteins, Non-Histone > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > CCCTC-Binding Factor

Preferred term

CCCTC-Binding Factor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CTCF, DNA-Binding Protein
  • CTCF Protein
  • DNA Binding Protein CTCF
  • DNA-Binding Protein CTCF

Scope note

  • A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.

History note

  • 2018 (1998)

In other languages

URI

http://www.yso.fi/onto/mesh/D000076246

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/29/17