Concept information
Preferred term
Heat Shock Transcription Factors
Type
-
Topical Descriptor
Entry terms
- Heat Shock Transcription Factor
Scope note
- Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3' pentamer DNA sequences and are regulated by POLY-ADP-RIBOSYLATION. They play essential roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.
History note
- 2018 (1992)
In other languages
-
Finnish
-
lämpöshokkitranskriptiotekijät
URI
http://www.yso.fi/onto/mesh/D000076249
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