Concept information
Preferred term
Irinotecan
Type
-
Topical Descriptor
Broader concept
Entry terms
- Camptothecin 11
- Camptothecin-11
- Irrinotecan
Scope note
- A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
History note
- 2019 (1987)
In other languages
-
Finnish
-
irinotecanum
-
Swedish
-
Campto
URI
http://www.yso.fi/onto/mesh/D000077146
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