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Concept information

Preferred term

Granulins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Epithelin
  • Epithelins
  • Granulin
  • Granulin Peptides

Note

  • do not confuse with the viral protein GRANULIN MATRIX PROTEINS see OCCLUSION BODY MATRIX PROTEINS

Scope note

  • Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc.

History note

  • 2019

In other languages

URI

http://www.yso.fi/onto/mesh/D000077155

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