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... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Benzene Derivatives > Phenylurea Compounds > Sorafenib
Organic Chemicals > Amides > Urea > Phenylurea Compounds > Sorafenib
Heterocyclic Compounds > Acids, Heterocyclic > Nicotinic Acids > Niacinamide > Sorafenib
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Nicotinic Acids > Niacinamide > Sorafenib

Preferred term

Sorafenib  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • BAY 43 9006
  • BAY 43-9006
  • BAY 439006
  • BAY 545 9085
  • BAY 545-9085
  • BAY 5459085
  • BAY 673472
  • BAY-673472
  • Nexavar
  • Sorafenib N Oxide
  • Sorafenib N-Oxide
  • Sorafenib Tosylate

Scope note

  • A niacinamide and phenylurea derivative that inhibits multiple intracellular and cell surface kinases thought to be involved in ANGIOGENESIS, including RAF KINASES and VEGF RECEPTORS. It is used in the treatment of advanced RENAL CELL CARCINOMA and HEPATOCELLULAR CARCINOMA, and for treatment of THYROID CARCINOMA refractory to radioactive iodine therapy.

History note

  • 2019 (2003)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077157

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